KPV

Overview
KPV is a tripeptide corresponding to the C-terminal fragment of α-MSH (alpha-melanocyte-stimulating hormone). It’s commonly explored in preclinical models of melanocortin signaling, epithelial barrier function, and controlled inflammatory readouts. We keep things straightforward: clean labeling, clarity-first specs, and access to batch documentation so you can verify exactly what you’re working with.

Key research highlights (in plain terms)

• Melanocortin pathway “on switch” — examined for activity at MC1R with downstream cAMP signaling, used to study how cells tune cytokine profiles (e.g., NF-κB–linked readouts) under standardized conditions.

• Barrier integrity models — applied in epithelial/keratinocyte systems to track tight-junction markers and TEER measurements related to barrier resilience.

• Cell migration & remodeling — used in wound-closure and scratch assays to observe cell motility and matrix-related markers during controlled remodeling phases.

• Innate defense panels — explored alongside antimicrobial/defense markers in vitro to map pathway effects on host-response signatures.

• Dose–response & selectivity — suited for building clear concentration–effect curves and comparing pathway selectivity versus other melanocortin fragments.

Why Pegasus

• Purity you can verify: batch testing with documentation (COA available)

• Clarity in every vial: straightforward specs and labeling

• Consistency you can trust: stable sourcing and careful handling

Specifications

• Form: Lyophilized powder

• Identity: Tripeptide fragment of α-MSH

• Sequence: Lys-Pro-Val (KPV)

• Appearance: White to off-white

• Purity: ≥98% (HPLC)

• Solubility: Sterile water or appropriate buffer (optimize per protocol)

• Packaging: Labeled vial with lot and batch ID

Storage & handling

• Store dry at −20 °C, protected from light and moisture

• After reconstitution, aliquot and store at −20 °C; avoid repeated freeze–thaw cycles

Included with your order

• Labeled vial of KPV (research grade)

• Batch/lot ID with access to testing details (COA)