Gonadorelin

Overview

Gonadorelin is a synthetic peptide analog of the naturally occurring gonadotropin-releasing hormone (GnRH). It is used in laboratory research to study the stimulation of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) secretion from the pituitary gland in preclinical models such as laboratory rodents. Researchers use Gonadorelin to investigate reproductive endocrinology, fertility pathways, and hormonal signaling mechanisms.

Benefits

Recent preclinical studies show that Gonadorelin can help stimulate the release of LH and FSH, making it a valuable compound for research focused on reproductive hormone regulation, fertility processes, and gonadal function in test subjects. Its precise and short-acting nature allows researchers to investigate time-specific hormonal responses.
Source: Thompson IR & Kaiser UB. GnRH pulse frequency-dependent differential regulation of LH and FSH gene expression. Frontiers in Endocrinology, 2014 (cited in 2023 review). For updated insight, see: Yoon S, et al. Mechanisms of pulsatile GnRH secretion. Frontiers in Endocrinology, 2022.

Possible Side Effects

In laboratory studies, test subjects administered Gonadorelin may exhibit mild side effects such as temporary injection site irritation, mild flushing, or slight changes in hormone-sensitive tissues depending on dosage and study duration. Effects vary by species and experimental design.
Source: Yoon S, et al., Frontiers in Endocrinology, 2022.

Dosage & Administration

Gonadorelin is typically administered via subcutaneous or intravenous injection under approved laboratory research protocols. Common research dosages range from 100 mcg to 500 mcg per injection, often given as single or multiple pulses daily depending on the study’s goal, test species, and hormonal response being investigated.
For laboratory research use only. Not for human consumption.

Summary

Gonadorelin is a synthetic GnRH analog peptide designed exclusively for laboratory research exploring reproductive hormone regulation, fertility pathways, and pituitary function in preclinical models. Research suggests it may stimulate LH and FSH release with mild side effects such as injection site irritation or flushing occasionally observed in test subjects. Gonadorelin is administered via subcutaneous or intravenous injection, with dosage and frequency tailored to the study’s design and species.
Strictly for research purposes only. Not for human use.