5-Amino-1MQ

Overview

5-Amino-1MQ (5-Amino-1-methylquinolinium) is a small molecule research compound studied for its potential to inhibit nicotinamide N-methyltransferase (NNMT), an enzyme involved in cellular energy regulation and fat metabolism. In laboratory settings, 5-Amino-1MQ is researched for its possible impact on energy expenditure, fat storage, and metabolic health in preclinical models such as laboratory rodents.

Benefits

Recent preclinical studies suggest that 5-Amino-1MQ may help reduce fat accumulation and promote increased energy expenditure by inhibiting NNMT, which can modulate key metabolic pathways. Researchers are investigating its role in obesity research, metabolic disorders, and studies related to cellular energy balance in test subjects.
Source: Kraus D, et al. Small molecule NNMT inhibitor activates thermogenic gene expression in adipose tissue. Nature Communications, 2019.

Possible Side Effects

In laboratory research, test subjects administered 5-Amino-1MQ may show mild side effects such as temporary changes in appetite-like behaviors, slight fluctuations in body weight markers, or minor digestive discomfort depending on dosage and study design. Effects vary based on species and experimental conditions.
Source: Kraus D, et al., Nature Communications, 2019.

Dosage & Administration

5-Amino-1MQ is typically administered orally or via injection under approved laboratory research protocols. Typical research dosages vary based on study design but commonly range from 10 mg to 50 mg per day, adjusted for the test species, study goals, and duration.
For laboratory research use only. Not for human consumption.

Summary

5-Amino-1MQ is a small molecule research compound developed exclusively for laboratory studies investigating NNMT inhibition, fat metabolism, and energy expenditure in preclinical models. Studies suggest it may help reduce fat storage and activate thermogenic pathways, with mild side effects such as appetite or digestive changes occasionally noted in test subjects. 5-Amino-1MQ is administered orally or by injection, with dosage and frequency customized to the study’s objectives and test species.
Strictly for research purposes only. Not for human use.