BAM-15

Overview

BAM-15 is a mitochondrial protonophore researched for its potential role as a mitochondrial uncoupler. In laboratory settings, BAM-15 is studied for its effects on energy expenditure, mitochondrial efficiency, and metabolic regulation in preclinical models such as laboratory rodents. Researchers investigate BAM-15 to better understand its impact on obesity, metabolic health, and mitochondrial dynamics.

Benefits

Recent preclinical research suggests that BAM-15 may help increase energy expenditure by uncoupling oxidative phosphorylation, leading to greater calorie burn and improved metabolic profiles in test subjects. Studies indicate that BAM-15 shows promise for reducing fat mass, improving insulin sensitivity, and protecting against diet-induced obesity in laboratory models.
Source: Alexopoulos SJ, et al. BAM15 reduces body weight, adiposity, and insulin resistance in mice. Nature Communications, 2020.

Possible Side Effects

In laboratory research, test subjects administered BAM-15 may show mild side effects such as slight changes in body temperature regulation, mild dehydration, or altered food intake depending on dosage, duration, and experimental design.
Source: Alexopoulos SJ, et al., Nature Communications, 2020.

Dosage & Administration

BAM-15 is typically administered orally or by intraperitoneal injection under approved laboratory research protocols. Typical research dosages in rodent models range from 5 mg/kg to 20 mg/kg daily, depending on the study’s design, species, and research objectives.
For laboratory research use only. Not for human consumption.

Summary

BAM-15 is a novel mitochondrial uncoupler peptide developed exclusively for laboratory research exploring energy expenditure, fat loss, and metabolic health in preclinical models. Research suggests it may help increase calorie burning and improve insulin sensitivity with mild side effects such as changes in temperature regulation occasionally noted in test subjects. BAM-15 is administered orally or via injection, with dosage and frequency tailored to each study’s goals and species.
Strictly for research purposes only. Not for human use.