LL-37

Overview

LL-37 is a naturally occurring antimicrobial peptide derived from the human cathelicidin family. It is studied in laboratory environments for its broad-spectrum antimicrobial, immunomodulatory, and wound-healing properties in preclinical models such as laboratory rodents. Researchers investigate LL-37 for its effects on host defense mechanisms, tissue repair, and inflammation modulation.

Benefits

Recent preclinical research suggests that LL-37 may help combat bacterial, viral, and fungal pathogens while also modulating inflammatory responses and promoting wound closure in test subjects. LL-37 is also studied for its potential to stimulate angiogenesis and enhance tissue regeneration in various models.
Source: Kahlenberg JM & Kaplan MJ. Little peptide, big effects: the role of LL-37 in inflammation and autoimmune disease. Journal of Immunology, 2018.

Possible Side Effects

In laboratory studies, test subjects administered LL-37 may exhibit mild side effects such as local injection site irritation, slight inflammatory responses at higher doses, or temporary changes in tissue reactivity, depending on dosage and study design.
Source: Kahlenberg JM & Kaplan MJ, Journal of Immunology, 2018.

Dosage & Administration

LL-37 is typically administered via subcutaneous injection, topical application, or intranasal delivery under approved laboratory research protocols. Typical research dosages range from 100 mcg to 1 mg per administration, depending on the study’s design, test species, and intended research outcomes.
For laboratory research use only. Not for human consumption.

Summary

LL-37 is an antimicrobial peptide developed exclusively for laboratory research investigating host defense, immune modulation, and wound healing in preclinical models. Research suggests it may help fight pathogens, reduce inflammation, and promote tissue regeneration with mild side effects such as injection site irritation occasionally observed in test subjects. LL-37 is administered by injection, topical application, or intranasal delivery, with dosage and frequency tailored to each study’s design and species.
Strictly for research purposes only. Not for human use.