MOTS-c

Overview

MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA type-c) is a mitochondrial-derived research peptide that plays a role in cellular metabolism regulation. It is studied in laboratory settings for its potential to influence metabolic pathways, energy balance, insulin sensitivity, and healthy aging in preclinical models such as laboratory rodents.

Benefits

Preclinical studies indicate that MOTS-c may help enhance glucose metabolism, improve insulin sensitivity, support healthy weight management, and promote mitochondrial function in research subjects. Researchers are particularly interested in its unique mitochondrial origin and its ability to regulate metabolic stress responses.
Source: Lee C, et al. The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance. Cell Metabolism, 2015. Link

Possible Side Effects

In laboratory research, test subjects administered MOTS-c have not shown significant adverse effects at research doses; however, possible side effects may include mild injection site irritation, transient changes in appetite, or minor fluctuations in energy markers depending on dosage and species.
Source: Lee C, et al., Cell Metabolism, 2015. Link

Dosage & Administration

MOTS-c is typically administered via subcutaneous injection under approved laboratory protocols. Common research dosing ranges from 5 mg to 15 mg per injection, with frequency varying from daily to multiple times per week depending on the study design and the species used.
For laboratory research use only. Not for human consumption.

Summary

MOTS-c is a mitochondrial-derived research peptide developed exclusively for laboratory studies exploring metabolic health, insulin sensitivity, and mitochondrial function in preclinical models. Research suggests it may help regulate energy balance and glucose metabolism with minimal side effects observed in test subjects. MOTS-c is usually administered by subcutaneous injection daily or several times per week, with dosage tailored to research objectives and the species involved.
Strictly for research purposes only. Not for human use.